PRODUCT DETAILS

About Applygen Soft Gelatin Vaginal Suppositories

CLINDAMYCIN+CLOTRIMAZOLE belongs to the class of medications called 'topical antibiotics' primarily used to treat vaginal infections, caused by bacteria (bacterial vaginosis), and yeast infection (candidiasis), and parasitic infections (trichomoniasis). Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Symptoms of a vaginal infection include itching, odor, and abnormal heavy white discharge from the vagina.

CLINDAMYCIN+CLOTRIMAZOLE comprises two medicines, namely: 'Clindamycin' (antibiotic) and 'Clotrimazole' (antifungal). Clindamycin belongs to the lincomycin antibiotic group that works by inhibiting bacterial protein synthesis, required for the survival of the bacteria. As a result, it inhibits bacterial growth but does not kill them (bacteriostatic effect). On the other hand, Clotrimazole belongs to the imidazole antifungal group that kills fungi by causing holes in its cell membrane, thereby leaking all content out. 

CLINDAMYCIN+CLOTRIMAZOLE is available in the form of a vaginal tablet, suppository, gel, and wash. These formulations are meant for vaginal use only. Common side effects of CLINDAMYCIN+CLOTRIMAZOLE include burning sensation, irritation, and itching in the vaginal area. However, these side effects are mild and temporary in nature and go off sometimes after applying to the affected area.  

Inform your doctor if you are allergic to any antibacterial, antifungal, clotrimazole, clindamycin, or any of its components. It is essential to tell your doctor if you use any other azole antifungal or lincomycin antibiotics agents before using CLINDAMYCIN+CLOTRIMAZOLE, otherwise using other antifungal or antibacterial may lead to overdose and toxicity. Let your doctor know if have any liver, kidney, or gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS). Clotrimazole and mineral oil additive in CLINDAMYCIN+CLOTRIMAZOLE may weaken rubber product's activities of contraceptive devices latex condoms, diaphragms, and cervical caps. Sometimes, antibiotic medications can cause antibiotic resistance. In such cases, your doctor may prescribe other antibiotics you are not resistant to.

Uses of Applygen Soft Gelatin Vaginal Suppositories

Vaginal infections

Medicinal Benefits of Applygen Soft Gelatin Vaginal Suppositories

CLINDAMYCIN+CLOTRIMAZOLE is used to treat vaginal infections like bacterial vaginosis (BV), candidiasis, and trichomoniasis. It comprises two medicines: 'Clindamycin' (antibiotic) and 'Clotrimazole' (antifungal). Clindamycin is an antibiotic drug and works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction. Clotrimazole is an imidazole antifungal medication that stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Together CLINDAMYCIN+CLOTRIMAZOLE treats vaginal infections caused by bacteria, yeast, and parasites preventing white discharge, itchiness, and inflammation in the genitourinary area. 

Directions for Use

CLINDAMYCIN+CLOTRIMAZOLE is available in the form of a vaginal tablet, suppository, gel, and wash. Wash your hands before and after using CLINDAMYCIN+CLOTRIMAZOLE. Vaginal tablet/Suppository/Gel: Vaginal tablet/suppository/gel usually comes with applicators. Take a tablet/ suppository/advised amount of gel and place it on the applicator. Lie relaxed on your back. Gently insert the applicator tip into the vagina and push the plunger to release the gel/tablet/ suppository into the vagina. If you are inserting CLINDAMYCIN+CLOTRIMAZOLE without an applicator, place the gel/tablet/ suppository on your clean finger and gently insert it into the vagina. Vaginal Wash: Take the advised amount of vaginal wash and massage gently on the vaginal area to produce lather. Rinse off with clean water.

Side Effects of Applygen Soft Gelatin Vaginal Suppositories

Like every medicine, CLINDAMYCIN+CLOTRIMAZOLE has common side effects like burning sensation, irritation, and itching in the vaginal area. These side effects do not require medical attention and gradually resolve during treatment. If you experience any side effects like pain while urinating, menstrual problems, abnormal vaginal bleeding, severe dizziness, and trouble breathing, please seek medical support. 

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using CLINDAMYCIN+CLOTRIMAZOLE. Do not use CLINDAMYCIN+CLOTRIMAZOLE if you are allergic to CLINDAMYCIN+CLOTRIMAZOLE or any of its components. Let your doctor know if have any liver, kidney, or gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS). It is advised to use CLINDAMYCIN+CLOTRIMAZOLE under your doctor's supervision if you use other azole antifungal medicines. Clotrimazole and mineral oil additive in CLINDAMYCIN+CLOTRIMAZOLE may weaken rubber product's activity (such as latex condoms, diaphragms, cervical caps).

Drug Interactions

Drug-Drug Interaction:

CLINDAMYCIN+CLOTRIMAZOLE may interact with anesthetic agents/skeletal muscle relaxants (atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, vecuronium, succinylcholine, tubocurarine, and metocurine) and respiratory drugs (budesonide, formoterol). 

Drug-Disease Interaction:

Before taking CLINDAMYCIN+CLOTRIMAZOLE, let your doctor know if have any liver, kidney, and gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS).

Safety Advice

ALCOHOL

No interaction was found/established.

PREGNANCY

There are limited studies on how CLINDAMYCIN+CLOTRIMAZOLE affects the unborn baby during pregnancy. It is advised to use CLINDAMYCIN+CLOTRIMAZOLE after consulting your doctor.

BREAST FEEDING

There is limited data on how CLINDAMYCIN+CLOTRIMAZOLE affects breastfeeding infants. However, systemic absorption of CLINDAMYCIN+CLOTRIMAZOLE is negligible after topical and vaginal administration. Consult your doctor for further advice.

DRIVING

No interaction was found/established.

LIVER

Let your doctor know if you have any history of liver diseases before taking CLINDAMYCIN+CLOTRIMAZOLE.

KIDNEY

Let your doctor know if you have any history of kidney diseases before taking CLINDAMYCIN+CLOTRIMAZOLE.